Background & Objectives: In patients of aortic stenosis and regurgitation, pressure and volume effects on left ventricular function are occult and missed by routine echocardiography markers like ejection fraction (EF). Speckle tracking analysis by measuring global longitudinal strain and global circumferential strain seems to ascertain this occult LV function parameters at an early phase in a more comprehensive manner. Limited studies have examined these parameters pre/post aortic valve replacement (AVR). Methods: 94 consecutive patients with symptomatic severe aortic stenosis (AS) or aortic regurgitation (AR), planned for AVR were included (as per set inclusion criteria) along with 15 normal controls-15 months prospective study. Routine echocardiography and speckle tracking imaging was done at baseline (pre AVR) and post AVR at 1st week,1st month and 3rd month of follow up. Results: 90 patients completed study (70 in AS and 20 in AR group). In AS group mean values (+/- 2 standard deviations) of global longitudinal strain (GLS) improved from a baseline -10.9%(+/- 3.9) to -19.4% (+/-3.8) at 3rd month(p value < 0.0001 ). Mean values of global circumferential strain (GCS) too improved from -17.3% (+/-4.5) to -21.4%(+/-3.6) respectively(p value
Kaler, Gajinder Pal Singh; Mahla, Rakesh; Mahla, Himanshu; Choudhary, Sarita; Singh, Gurdarshan; Patel, Raghuveer Prasad; and Kaler, Navjot Kaur
"Speckle tracking echocardiographic assessment of left ventricular function by myocardial strain before and after aortic valve replacement,"
Journal of the Saudi Heart Association: Vol. 33
, Article 16.
Available at: https://doi.org/10.37616/2212-5043.1288
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