Authors

Kenzo Adhi Wiranata, Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University, Surakarta, IndonesiaFollow
Pramadya Vardhani Mustafiza, 1Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia
Enrico Ananda Budiono, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia

Ruptured Sinus of Valsalva Aneurysm in a Patient with Mixed Connective Tissue Disease: Case Report

Abstract

Sinus of Valsalva aneurysm is a rare cardiac anomaly, affecting approximately 0.09% of the population. Its rupture represents a life-threatening event that can rapidly lead to heart failure. We report a 32-year-old woman with mixed connective tissue disease presenting with right-sided heart failure. Echocardiography demonstrated a ruptured right coronary cusp sinus of valsalva aneurysm into the right ventricle with moderate aortic regurgitation. Surgical repair was successfully performed, and histopathology supported an autoimmune-mediated etiology. To our knowledge, this is the first reported case of ruptured sinus of valsalva aneurysm occurring in a patient with autoimmune mixed connective tissue disease.

Recommended Citation

Wiranata, Kenzo Adhi; Mustafiza, Pramadya Vardhani; and Budiono, Enrico Ananda (2026) "Ruptured Sinus of Valsalva Aneurysm in a Patient with Mixed Connective Tissue Disease: Case Report," Journal of the Saudi Heart Association: Vol. 38 : Iss. 1 , Article 3.
Available at: https://doi.org/10.37616/2212-5043.1472

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